Scientific Literature

Autophagy: molecular mechanisms and disease outcomes
Daniel J. Klionsky and Vojo Deretic
During autophagy, double-membrane structures called autophagosomes engulf cytosol or organelles and deliver them to lysosomes (in mammalian cells) or the vacuole …

How Cell Clean House
Daniel J. Klionsky and Vojo Deretic
Worn-out proteins, malfunctioning organelles, invading microorganisms: all are swept up by tiny internal “vacuum cleaners” that keep a living cell healthy. If the process, called autophagy, can be …

Autophagy in Human Health and Disease
Augustine M.K. Choi, M.D., Stefan W. Ryter, Ph.D., and Beth Levine, M.D.
Worn-out proteins, malfunctioning organelles, invading microorganisms: all are swept up by tiny internal “vacuum cleaners” that keep a living cell healthy. If the process, called autophagy, can be …

Autophagy: for better or for worse
Ellen Wirawan, Tom Vanden Berghe, Saskia Lippens, Patrizia Agostinis, Peter Vandenabeele
Cells have mechanisms that clear out superfluous, misfolded, damaged and harmful proteins: the ubiquitinproteasome degradation pathway and autophagy¬†…

Autophagy Journals
Editor-in-Chief: Daniel J. Klionsky
Guidelines for the use and interpretation of assays for monitoring autophagy …

Autophagy: The Higgs Particle of Biology?
drugbaron
With all the excitement surrounding the discovery of a particle that might be the elusive Higgs Boson this week, it set DrugBaron wondering what might be the equivalent in biology …